On Thanksgiving Day, The Murray Family gets a phone call from the President warning them that nuclear war is eminent. In a tiny South American country called Vespugia, vicious dictator nicknamed Mad Dog Branzillo sits poised with his finger on the button. Meg's mother in-law, the reclusive Mrs. O'Keefe, charges Meg's 15 year old brother, old soul Charles Wallace, with an ancient rune of protection and with the task of averting the end of the world. Charles Wallace must journey through time and space and the bodies of many different people to find the 'what might of been' that will change the past to change the future.REREAD.I read this book in a couple of hours. It was always my favorite of the series, along with 'Many Waters'. This may have only been my second time reading it since I was in high school, but it always stuck with me. It does read a bit differently, now that I'm older, but I still love the simple core of the story: that we're all interconnected, since the very beginnings of time, and that every thing we do matters, and every choice is a victory for the side of joy or the despair.